What is PDO?

'Polydioxanone'

PDO thread

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What is PDO?

Abbreviation of polydioxanone
Colorless crystal form, biodegradable synthetic polymer
Monofilament
Degradable by hydrolysis
Mainly excreted by urine
Period of biodegradation: 6-8 months

PDO thread

PDO is an abbreviation of polydioxanone, and is widely used as surgery stitch thread which is also safe to human body. As a colorless biodegradable synthetic polymer, it is a monofilament, so hydrolyzed in body and then naturally excreted by urine within 6 months. Thus, PDO is safe to human body. PDO procedure leads to mechanotransduction within skin by forming vector among fine threads (FT) when FT is inserted in a fixed direction. Inserted PDO operates in the cell as mechanical external stimulus, and brings about the following effects by providing external stimulus within skin.

  1. Production of collagen
  2. Circulation of microvessel
  3. Increase of cell metabolism
  4. Surrounding tissue adhesion
  5. Surrounding tissue anchoring
  6. Decrease of cellulite
  7. Relaxation of muscles
  8. Increase of lipolysis
  9. Inducement of skin regeneration
  10. Regeneration and cellular activities of skin and subcutaneous tissue
  11. More than 300 times increase of EGF
  12. More than 350 times increase of FGF
  13. More than 400 times increase of IGF
  14. More than 150 times increase of TGF-ß
  15. More than 1000 times increase of VEGF